Publications

El Khawanky N, Hughes A, Yu W, Myburgh R, Matschulla T, Taromi S, Aumann K, Clarson J, Vinnakota JM, Shoumariyeh K, Miething C, Lopez AF, Brown MP, Duyster J, Hein L, Manz MG, Hughes TP, White DL, Yong ASM, Zeiser R: Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia. Nat Commun 12(1), 6436, doi: 10.1038/s41467-021-26683-0 (2021).

Erny D, Dokalis N, Mezö C, Castoldi A, Mossad O, Staszewski O, Frosch M, Villa M, Fuchs V, Mayer A, Neuber J, Sosat J, Tholen S, Schilling O, Vlachos A, Blank T, Gomez de Agüero M, Macpherson AJ, Pearce EJ, Prinz M: Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease. Cell Metab 33(11); 2260-2276.e7 (2021).

Sankowski R, Ahmari J, Mezö C, Hrabě de Angelis AL, Fuchs V, Utermöhlen O, Buch T, Blank T, Gomez de Agüero M, Macpherson AJ, Erny D: Commensal microbiota divergently affect myeloid subsets in the mammalian central nervous system during homeostasis and disease. EMBO J, e108605; doi: 10.15252/embj.2021108605 (2021).

Zhang P, Schlecht A, Wolf J, Boneva S, Laich Y, Koch J, Ludwig F, Boeck M, Thien A, Härdtner C, Kierdorf K, Agostini H, Schlunck G, Prinz M, Hilgendorf I, Wieghofer P & Lange C: The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation. Journal of Neuroinflammation 18, 215 (2021).

Klammer MG, Dzaye O, Wallach T, Krüger C, Gaessler D, Buonfiglioli A, Derkow K, Kettenmann H, Brinkmann MM, Lehnardt S: UNC93B1 is widely expressed in the murine CNS and is required for neuroinflammation and neuronal injury induced by microRNA let-7b. Front Immunol 12:715774 (2021).

Ifuku M, Hinkelmann L, Kuhrt LD, Efe IE, Kumbol V, Buonfiglioli A, Krüger C, Jordan P, Fulde M, Noda M, Kettenmann H*, Lehnardt S*: Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury. Acta Neuropathol Commun 8(1):159 (2020). *Equal contribition.

Acera MG, Bubeck M, Mascia F, Diemand L, Sturm G, Kühl AA, Atreya R, Lie DC, Neurath MF, Schumann M, Klose CSN, Trajanoski Z, Becker C and Patankar JV. Dynamic, Transient, and Robust Increase in the Innervation of the Inflamed Mucosa in Inflammatory Bowel Diseases. Cells 10(9), 2253 (2021).

Haimon Z, Frumer G, Kim J-S, Haffner-Krausz R, Ben-Dor S, Porat Z, Chappell-Maor L, Boura-Halfon S, Jung S: Microglia Control CNS T Regulatory Cell Activity During Remission From EAE Pathology. Available at SSRN: https://ssrn.com/abstract=3911553 or http://dx.doi.org/10.2139/ssrn.3911553 (2021).

Jakob MO, Deshpande D, Murugan S, and Klose CSN. An integrated view on neuronal subsets in the peripheral nervous system and their role in immunoregulation. Front Immunol. 12;12:679055 (2021).

Raden M*, Wallach T*, Miladi M*, Zhai Y, Krüger C, Mossmann ZJ, Dembny P, Backofen R*, Lehnardt S*: Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands. RNA Biol 1-10; doi: 10.1080/15476286.2021.1940697 (2021). *Equal contribition.

Mossad O, Blank T: Getting on in Old Age: How the Gut Microbiota Interferes With Brain Innate Immunity. Front Cell Neurosci 15, 698126 (2021).

Pinkert S, Kespohl M, Kelm N, Kaya Z, Heuser A, Klingel A, Beling A: Exploration of Analgesia with Tramadol in the Coxsackievirus B3 Myocarditis Mouse Model. Viruses 13(7):1222; doi: 10.3390/v13071222 (2021).

Kienle K, Glaser KM, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, Epple MW, Gunzer M, Baumeister R, Tarrant TK, Germain RN, Irimia D, Kastenmüller W, Lämmermann T: Neutrophils self-limit swarming to contain bacterial growth in vivo. Science 372(6548):eabe7729; doi: 10.1126/science.abe7729 (2021).

Galanis C, Fellenz M, Becker D, Bold C, Lichtenthaler SF, Müller UC, Deller T and Vlachos A: Amyloid-Beta Mediates Homeostatic Synaptic Plasticity. J Neurosci 41(24):5157-5172; doi: 10.1523/JNEUROSCI.1820-20.2021 (2021).

Baasch S, Giansanti P, Kolter J, Riedl A, Forde AJ, Runge S, Zenke S, Elling R, Halenius A, Brabletz S, Hengel H, Kuster B, Brabletz T, Cicin-Sain L, Arens R, Vlachos A, Rohr JC, Stemmler MP, Kopf M, Ruzsics Z, Henneke P: Cytomegalovirus subverts macrophage identity. Cell 184, 1-20 (2021).

Schwabenland M, Salié H, Tanevski J, Killmer S, Salvat Lago M, Schlaak AE, Mayer L, Matschke J, Püschel K, Fitzek A, Ondruschka B, Mei HE, Boettler T, Neumann-Haefelin C, Hofmann M, Breithaupt A, Genc N, Stadelmann C, Saez-Rodriguez J, Bronsert P, Knobeloch K-P, Blank T, Thimme R, Glatzel M, Prinz M, Bengsch B: Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T cell interactions. Immunity; doi: https://doi.org/10.1016/j.immuni.2021.06.002 (2021).