Projects : SFB/TRR 167

Project Area A: Factors regulating the fate and function of brain macrophages

Prof. Dr. Marco Prinz

Definition of context-specific microglia states and the pathways involved by single-cell profiling

Prof. Steffen Jung

Dissecting differential functional contributions of parenchymal and nonparenchymal brain macrophages

Prof. Dr. Ido Amit
Dr. Hadas Keren-Shaul

Applications of advanced single-cell genomic technologies to characterize the role of microglia and their cellular interactions in neurodegenerative diseases

Dr. Tim Lämmermann
Dr. Angelika Rambold

The sequential phases of apoptotic cell clearance by microglia and macrophages

Prof. Dr. Daniel Erny
PD Dr. Thomas Blank

How the gut microbiota controls CNS macrophages during aging and agerelated neurodegenerative diseases

Prof. Dr. Olaf Groß

The NLRP3 inflammasome in CNS homeostasis and disease

Juniorprof. Dr. Katrin Kierdorf

Deciphering molecular recruitment mechanisms of microglial progenitors during development

Prof. Dr. Christian Madry

Importance of microglial tissue surveillance for neural development and function

Project Area B: Myeloid cells in brain diseases

Prof. Dr. Seija Lehnardt

Role of microRNAs as modulators of microglial function on neurodegeneration

Prof. Dr. Philipp Henneke

Macrophage programming in viral encephalitis

PD.Dr. Chotima Böttcher

Dynamic compartmentalization of myeloid cell responses in neuroinflammation

Prof. Dr. Robert Zeiser

The role of microglia during immunotherapy-induced neuroinflammation

Prof. Dr. Josef Priller

Circadian regulation of myeloid cell function in neurodegenerative diseases

Prof. Dr. Andreas Meisel
Dr. Christian Meisel

Dissecting the crosstalk between myeloid cells, pericytes and lymphocytes for autoimmune-mediated mechanisms underlying post-stroke cognitive decline

Prof. Dr. Andreas Vlachos

Cellular and molecular mechanisms of microglia-mediated homeostatic synaptic plasticity

PD Dr. Klaus-Peter Knobeloch
Prof. Dr. Antje Beling

USP18 as a key regulator for microglia activation

Dr. Christoph Klose

Adrenergic regulation of myeloid cells in chronic inflammation and neurodegeneration

Dr. Antigoni Triantafyllopoulou

Regulation of CNS Lupus by brain macrophages

Integrated Research Training Group

Prof. Dr. Josef Priller

NeuroMac School

Core Projects

Prof. Dr. Rolf Backofen
Prof. Dr. Dr. Melanie Börries

Bioinformatics core

Get in contact

Coordinator
Tanja Wilde, M.A.
Medical Center – University of Freiburg

+49 (0)761 / 270-51190 tanja.wilde@uniklinik-freiburg.de

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