Publications

Paterson N and Lämmermann T: Macrophage network dynamics depend on haptokinesis for optimal local surveillance. Elife 11, e75354, doi: 10.7554/eLife.75354 (2022).

Erny D, Dokalis N, Mezö C, Mossad O, Blank T, Prinz M: Flow-cytometry-based protocol to analyze respiratory chain function in mouse microglia. STAR Protoc 3(1):101186; doi: 10.1016/j.xpro.2022.101186 (2022).

Falkai P, Koutsouleris N, Bertsch K, Bialas M, Binder E, […], Priller J: Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health. Front Psychiatry 13, 815718, doi: 10.3389/fpsyt.2022.815718 (2022).

Munro, DAD, Movahedi, K, & Priller, J. Macrophage compartmentalization in the brain and cerebrospinal fluid system. Sci Immunol, 7(69):eabk0391. https://doi: 10.1126/sciimmunol.abk0391 (2022).

Mossad O, Batut B, Yilmaz B, Dokalis N, Mezö C, Nent E, Nabavi LS, Mayer M, Mocayar Maron FJ, Buescher JM, Gomez de Agüero M, Szalay A, Lämmermann T, Macpherson AJ, Ganal-Vonarburg SC, Backofen R, Erny D, Prinz M & Blank T: Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine. Nature Neuroscience 25, 295–305 (2022).

Cohen M, Giladi A, Barboy O, Hamon P, Li B, Zada M, Gurevich-Shapiro A, Beccaria CG, David E, Maier BB, Buckup M, Kamer I, Deczkowska A, Le Berichel J, Bar J, Iannacone M, Tanay A, Merad M, Amit I: The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response. Nat Cancer 3(3), 303-317, doi: 10.1038/s43018-022-00338-5 (2022).

Salomon R, Rotem H, Katzenelenbogen Y, Weiner A, Saban NC, Feferman T, Amit I, Dahan R: Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting. Nat Cancer 3(3), 287-302, doi: 10.1038/s43018-022-00329-6 (2022).

Ravi VM, Neidert N, Will P, Joseph K, Maier JP, Kückelhaus J, Vollmer L, Goeldner JM, Behringer SP, Scherer F, Boerries M, Follo M, Weiss T, Delev D, Kernbach J, Franco P, Schallner N, Dierks C, Carro MS, Hofmann UG, Fung C, Sankowski R, Prinz M, Beck J, Salié H, Bengsch B, Schnell O and Heiland DH: T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10. Nat Commun 13: 925; doi: 10.1038/s41467-022-28523-1 (2022).

Kasapi A, Triantafyllopoulou A: Genotoxic stress signalling as a driver of macrophage diversity. Cell Stress 6(3), 30-44, doi: 10.15698/cst2022.03.265 (2022).

Sankowski R, Monaco G, Prinz M: Evaluating microglial phenotypes using single-cell technologies. Trends Neurosci 45(2):133-144; doi: 10.1016/j.tins.2021.11.001 (2022).

Voss M, Kleinau G, Gimber N, Janek K, Bredow C, Thery F, Impens F, SchmoranzeJ, Scheerer P, Kloetzel P-M, Beling A: A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A. FEBS J 289(13), 3826-3838, doi: 10.1111/febs.16368 (2022).

Lopes KdP, Snijders GJL, Humphrey J, Allan A, Sneeboer MAM, Navarro E, Schilder BM, Vialle RA, Parks M, Missall R, van Zuiden W, Gigase FAJ, Kübler R, van Berlekom AB, Hicks EM, Bӧttcher C, Priller J, Kahn RS, de Witte LD, Raj T: Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies. Nat Genet 54(1), 4-17 (2022).

Suwala AK, Felix M, Friedel D, Stichel D, Schrimpf D, Hinz F, Hewer E, Schweizer L, Dohmen H, Pohl U, Staszewski O, Korshunov A, Stein M, Wongsurawat T, Cheunsuacchon P, Sathornsumetee S, Koelsche C, Turner C, Le Rhun E, Mühlebner A, Schucht P, Özduman K, Ono T, Shimizu H, Prinz M, Acker T, Herold-Mende C, Kessler T, Wick W, Capper D, Wesseling P, Sahm F, von Deimling A, Hartmann C, Reuss DE: Oligosarcomas, IDH-mutant are distinct and aggressive. Acta Neuropathol 143(2):263-281; doi: 10.1007/s00401-021-02395-z (2022).

Mossad O, Nent E, Woltemate S, Folschweiller S, Buescher JM, Schnepf D, Erny D, Staeheli P, Bartos M, Szalay A, Stecher B, Vital M, Sauer JF, Lämmermann T, Prinz M, Blank T: Microbiota-dependent increase in δ-valerobetaine affects neuronal synchronicity and mediates age-related cognitive decline. Nature Aging 1, 1127-1136 (2021).

Wallach T*, Mossmann ZJ*, Szczepek M, Wetzel M, Machado R, Raden M, Miladi M, Kleinau G, Krüger C, Dembny P, Adler D, Zhai Y, Kumbol V, Dzaye O, Schüler J, Futschik M, Backofen R, Scheerer P, Lehnardt S: MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration.
Mol Neurodegener 16(1):80 (2021). *equal contribution

d’Errico P, Ziegler-Waldkirch S, Aires V, Hoffmann P, Mezö C, Erny D, Sebastian Monasor L, Liebscher S, Ravi VM, Joseph K, Schnell O, Kierdorf K, Staszewski O, Tahirovic S, Prinz M, Meyer-Luehmann M: Microglia contribute to the propagation of Aβ into unaffected brain tissue. Nat Neurosci 25(1):20-25; doi: 10.1038/s41593-021-00951-0 (2021).