Publications

Giacomello G, Otto C, Priller J, Ruprecht K, Böttcher C, Parr MK: 1,2-13C2-Glucose Tracing Approach to Assess Metabolic Alterations of Human Monocytes under Neuroinflammatory Conditions. Curr Issues Mol Biol 45(1):765-781; doi: 10.3390/cimb45010051 (2023).

Wallach T, Raden M, Hinkelmann L, Brehm M, Rabsch D, Weidling H, Krüger C, Kettenmann H, Backofen R, Lehnardt S: Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia. Front Immunol, 13; doi.org/10.3389/fimmu.2022.1066456 (2023).

Faust TE, Feinberg PA, O’Connor C, Kawaguchi R, Chan A, Strasburger H, Masuda T, Amann L, Knobeloch KP, Prinz M, Schaefer A and Schafer DP: A comparative analysis of microglial inducible Cre lines. bioRxiv; doi: 10.1101/2023.01.09.523268 (2023).

Rapp J, Jung M, Klar RFU, Wolf J, Arnold J, Gorka O, Groß O, Lange C, Agostini H, Schlunck G, Bucher F: STAT3 signaling induced by the IL-6 family of cytokines modulates angiogenesis. J Cell Sci 136(1):jcs260182; doi: 10.1242/jcs.260182 (2023).

McNamara, NB, Munro, DAD, Bestard-Cuche, N, Uyeda, A, Bogie, JFJ, Hoffmann, A, Holloway, RK, Molina-Gonzalez, I, Askew, KE, Mitchell, S, Mungall, W, Dodds, M, Dittmayer, C, Moss, J, Rose, J, Szymkowiak, S, Amann, L, McColl, BW, Prinz, M, Spires-Jones, TL, Stenzel, W, Horsburgh, K, Hendriks, JJA, Pridans, C, Muramatsu, R, Williams, A, Priller, J*, & Miron, VE*. Microglia regulate central nervous system myelin growth and integrity. Nature, 613(7942):120-129. https://doi: 10.1038/s41586-022-05534-y (2023).

Haimon Z, Frumer GR, Kim J-S, Trzebanski S, Haffner-Krausz R, Ben-Dor S, Porat Z, Muschaweckh A, Chappell-Maor L, Boura-Halfon S, Korn T & Jung S: Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology. Nature Immunology, https://doi.org/10.1038/s41590-022-01360-6 (2022).

Fernández Zapata C, Giacomello G, Spruth EJ, Middeldorp J, Gallaccio G, Dehlinger A, Dames C, Leman JKH, van Dijk RE, Meisel A, Schlickeiser S, Kunkel D, Hol EM, Paul F, Parr MK, Priller J, and Böttcher C: Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer’s disease. Nat Commun 13: 7210, doi: 10.1038/s41467-022-34719-2 (2022).

Ferrarese R, […], Prinz M, Pelicci G, Kammerer B, Boerries M, Carro MS: ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma. Glia, doi: 10.1002/glia.24299 (2022).

Carvalho LAR, Ross B, Fehr L, Bolgi O, Wöhrle S, Lum KM, Podlesainski D, Vieira AC, Kiefersauer R, Félix R, Rodrigues T, Lucas SD, Groß O, Geiss-Friedlander R, Cravatt BF, Huber R, Kaiser M, Moreira R: Chemoproteomics-Enabled Identification of 4-Oxo-β-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew Chem Int Ed Engl 61(47), e202210498, doi: 10.1002/anie.202210498 (2022).

Locatelli G, Marques-Ferreira F, Katsoulas A, […] Prinz M, Tresch A, Becher B, Buch T: IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia, doi: 10.1002/glia.24299 (2022).

Paolicelli RC, Sierra A, Stevens B, [..] Amit I, […] Jung, S, […] Priller J, Prinz M, […] Wyss-Coray T: Microglia states and nomenclature: A field at its crossroads. Neuron 110(21), 3458-3483, doi: 10.1016/j.neuron.2022.10.020 (2022).

Jarick KJ, Topczewska PM, Jakob MO, Yano H, Arifuzzaman M, Gao X, Boulekou S, Stokic-Trtica V, Leclère PS, Preußer A, Rompe ZA, Stamm A, Tsou AM, Chu C, Heinrich FR, Guerra GM, Durek P, Ivanov A, Beule D, Helfrich S, Duerr CU, Kühl AA, Stehle C, Romagnani C, Mashreghi MF, Diefenbach A, Artis D, Klose CSN: Non-redundant functions of group 2 innate lymphoid cells. Nature 611(7937), 794-800, doi: 10.1038/s41586-022-05395-5 (2022).

Tsou AM, Yano H, Parkhurst CN, Mahlakõiv T, Chu C, Zhang W, He Z, Jarick KJ, Zhong C, Putzel GG, Hatazaki M; JRI IBD Live Cell Bank Consortium, Lorenz IC, Andrew D, Balderes P, Klose CSN, Lira SA, Artis D: Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. Nature 611(7937), 787-793. doi: 10.1038/s41586-022-05297-6 (2022).

Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Groß O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB: Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis. Cardiovasc Res 118(13):2778-2791. doi: 10.1093/cvr/cvab337 (2022).

Cook J and Prinz M: Regulation of microglial physiology by the microbiota. Gut Microbes 14(1):2125739, doi: 10.1080/19490976.2022.2125739 (2022).

Ho JNHG, Schmidt D, Lowinus T, […] Zeiser R: Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140(10), 1167-1181, doi: 10.1182/blood.2022016082 (2022).