Publications

Baasch S, Ruzsics Z and Henneke P: Cytomegaloviruses and Macrophages—Friends and Foes From Early on? Front Immunol 11 (793), doi: 10.3389/fimmu.2020.00793 (2020).

Drost N, Houtman J, Cseresnyés Z, Niesner R, Rinnenthal JL, Miller KR, Prokop S and Heppner FL: The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin. Sci Rep 10: 7152, doi: 10.1038/s41598-020-63989-3 (2020).

Schlecht A, Boneva S, Gruber M, Zhang P, Horres R, Bucher F, Auw-Haedrich C, Hansen L, Stahl A, Hilgendorf I, Agostini H, Wieghofer P, Schlunck G, Wolf J, Lange CAK: Transcriptomic Characterization of Human Choroidal Neovascular Membranes Identifies Calprotectin as a Novel Biomarker for Patients With Age-Related Macular Degeneration. Am J Pathol S0002-9440(20)30201-7, doi: 10.1016/j.ajpath.2020.04.004 (2020).

Amann L, Prinz M: The origin, fate and function of macrophages in the peripheral nervous system – an update. In Immunol  32(11), 709-717 (2020).

Ydens E, Amann L, Asselbergh B, Scott CL, Martens L, Sichien D, Mossad O, Blank T, De Prijck D, Low D, Masuda T, Saeys Y, Timmerman V, Stumm R, Ginhoux F, Prinz M, Janssens S and Guilliams M: Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury. Nature Neuroscience 23, 676–689 (2020).

Dembny P, Newman AG, Singh M, Hinz M, Szczepek M, Krüger C, Adalbert R, Dzaye O,Trimbuch T, Wallach T, Kleinau G, Derkow K, Richard BC, Schipke C, Scheidereit C, Stachelscheid H, Golenbock D, Peters O, Coleman M, Heppner FL, Scheerer P, Tarabykin V, Ruprecht K, Izsvák Z, Mayer J, and Lehnardt S: Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. JCI Insight 5(7): e131093, doi: 10.1172/jci.insight.131093 (2020).

Hamarsheh S, Osswald L, Saller BS, Unger S, De Feo D, Vinnakota JM, Konantz M, Uhl FM, Becker H, Lübbert M, Shoumariyeh K, Schürch C, Andrieux G, Venhoff N, Schmitt-Graeff A, Duquesne S, Pfeifer D, Cooper MA, Lengerke C, Boerries M, Duyster J, Niemeyer CM, Erlacher M, Blazar BR, Becher B, Groß O, Brummer T and Zeiser R: Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation. Nature Communications 11, 1659 (2020).

Duscha A, Gisevius B, Hirschberg S, Yissachar N, Stangl GI, Eilers E, Bader V, Haase S, Kaisler J, David C, Schneider R, Troisi R, Zent D, Hegelmaier T, Dokalis N, Gerstein S, Del Mare-Roumani S, Amidror S, Staszewski O, Poschmann G, Stühler K, Hirche F, Balogh A, Kempa S, Träger P, Zaiss MM, Holm JB, Massa MG, Nielsen HB, Faissner A, Lukas C, Gatermann SG, Scholz M, Przuntek H, Prinz M, Forslund SK, Winklhofer KF, Müller DN, Linker RA, Gold R, Haghikia A: Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism. Cell,  180(6),1067-1080.e16 8 (2020).

Erny D, Prinz M: How microbiota shape microglial phenotypes and epigenetics. Glia 68(8), 1655-1672. doi: 10.1002/glia.23822 (2020).

Marschner D, Falk M, Javorniczky NR, Hanke-Müller K, Rawluk J, Schmitt-Graeff A, Simonetta F, Haring E, Dicks S, Ku M, Duquesne S, Aumann K, Rafei-Shamsabadi D, Meiss F, Marschner P, Boerries M, Negrin RS, Duyster J, Zeiser R, and Köhler N: MicroRNA-146a regulates immune-related adverse events caused by immune checkpoint inhibitors. JCI Insight 5(6), e132334 (2020).

Hotter B, Hoffmann S, Ulm L, Montaner J, Bustamante A, Meisel C, Meisel A: Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke. Biomarkers for predicting pneumonia, functional outcome, and death after stroke. Neurol Neuroimmunol Neuroinflamm 7(3): e692, doi: 10.1212/NXI.0000000000000692 (2020).

Kierdorf K, Hersperger F, Sharrock J, Vincent CM, Ustaoglu P, Dou J, Gyoergy A, Groß O, Siekhaus DE, Dionne MS: Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila. Elife 9. pii: e51595 (2020).

Wallach T, Wetzel M, Dembny P, Staszewski O, Krüger C, Buonfiglioli A, Prinz M, Lehnardt S: Identification of CNS injury-related microRNAs as novel Toll-like Receptor 7/8 signaling ctivators by Small RNA Sequencing. Cells 9(1), pii: E186 (2020).

Kolter J, Kierdorf K, Henneke P: Origin and Differentiation of Nerve-Associated Macrophages. J Immunol 204, 271-289; doi: 10.4049/jimmunol.org/content/204/2/271 (2020).

Bell OH, Copland DA, AWard A, Nicholson LB, Lange CAK,Chu CJ and Dick AD: Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol 10 (3033), doi: 10.3389/fimmu.2019.03033 (2020).

Böttcher C, Fernández-Zapata C, Schlickeiser S, Kunkel D, Schulz AR, Mei HE, Weidinger C, Gieß RM, Asseyer S, Siegmund B, Paul F, Ruprecht K, Priller J: Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis. Sci Rep 9(1), 19471. doi: 10.1038/s41598-019-55852-x 8 (2019).