Publications

Saller BS, Wöhrle S, Fischer L, …, Schwemmle M, Groß CJ, Groß O: Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity; doi: 10.1016/j.immuni.2024.10.012 (2024).

Giesler S, Riemer R, Lowinus T, Zeiser R: Immune-mediated colitis after immune checkpoint inhibitor therapy . Trends Mol Med S1471-4914(24)00266-1; doi: 10.1016/j.molmed.2024.09.009 (2024).

Nath S, Martínez Santamaría JC, Chu Y-H, Choi JS, Conforti P, Lin J-D, Sankowski R, Amann L, Galanis C, Wu K, Deshpande SS, Vlachos A, Prinz M, Lee JK, Schachtrup C: Interaction between subventricular zone microglia and neural stem cells impacts the neurogenic response in a mouse model of cortical ischemic stroke. Nat Commun 15:9095. doi: 10.1038/s41467-024-53217-1 (2024).

Bøstrand SMK, Seeker LA, Bestard-Cuche N, Kazakou N-L, Jäkel S, Kenkhuis B,
Henderson NC, de Bot ST, van Roon-Mom WMC, Priller J and Williams A: Mapping the glial transcriptome in Huntington’s disease using snRNAseq: selective disruption of glial signatures across brain regions. Acta Neuropathol Commun 12:165; doi: 10.1186/s40478-024-01871-3 (2024).

Dumas AA, Gasull AD, Prinz M: Beyond borders: the choroid plexus-immune communication during neuroinflammation. Signal Transduct Target Ther 9:278. doi: 10.1038/s41392-024-01997-9 (2024).

Hasavci D, Blank T: A microglial compliment: controlling neuronal function from within. Signal Transduct Target Ther 9(1):267; doi: 10.1038/s41392-024-01989-9 (2024).

Schmidt D, Endres C, Hoefflin R, Andrieux G, Zwick M, Karantzelis N, Staehle HF, Vinnakota JM, Duquesne S, Mozaffari Jovein M, Pfeifer D, Becker H, Blazar BR, Zähringer A, Duyster J, Brummer T, Boerries M, Baumeister J, Shoumariyeh K, Li J, Green AR, Heidel FH, Tirosh I, Pahl HL, Leimkühler N, Köhler N, de Toledo MAS, Koschmieder S, Zeiser R: Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment. Cancer Res 84(18):2985-3003; doi: 10.1158/0008-5472.CAN-23-3553 (2024).

Früholz I, Meyer-Luehmann M: The intricate interplay between microglia and adult neurogenesis in Alzheimer’s disease . Front Cell Neurosci 18:1456253; doi: 10.3389/fncel.2024.1456253 (2024).

Lisowski P, Lickfett S, Rybak-Wolf A, Menacho C, Le S, Pentimalli TM, Notopoulou S, Dykstra W, Oehler D, López-Calcerrada S, Mlody B, Otto M, Wu M, Richter Y, Roth P, Anand R, Kulka LAM, Meierhofer D, Glazar P, Legnini I, Telugu NS, Hahn T, Neuendorf N, Miller DC, Böddrich A, Polzin A, Mayatepek E, Diecke S, Olzscha H, Kirstein J, Ugalde C, Petrakis S, Cambridge S, Rajewsky N, Kühn R, Wanker EE, Priller J, Metzger JJ & Prigione A: Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nat Commun 15:7027. doi: 10.1038/s41467-024-51216-w (2024).

Wogram E, Sümpelmann F, Dong W, Rawat E, Fernández Maestre I, Fu D, Braswell B, Khalil A, Buescher JM, Mittler G, Borner GHH, Vlachos A, Tholen S, Schilling O, Bell GW, Rambold AS, Akhtar A, Schnell O, Beck J, Abu-Remaileh M, Prinz M, Jaenisch R: Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity; doi:https://doi.org/10.1016/j.immuni.2024.07.019 (2024).

Biniaris-Georgallis S-I, Aschman T, Stergioula K, Schreiber F, Jafari V, Taranko A, Karmalkar T, Kasapi A, Rovis TL, Jelencic V, Bejarano DA, Fabry L, Papacharalampous M, Mattiola I, Molgora M, Hou J, Hublitz KW, Heinrich F, Guerra GM, Durek P, Patone G, Lindberg EL, Maatz H, Hölsken O, … Triantafyllopoulou A: Amplification of autoimmune organ damage by NKp46-activated ILC1s. Nature 634(8035):952-960; doi: 10.1038/s41586-024-07907-x (2024).

Topczewska PM, Savvopoulou A, Cosovanu C, Klose CSN: Transcriptional profiling identifies IL-33-expressing intestinal stromal cells as a signaling hub poised to interact with enteric neurons.
Front Cell Dev Biol 12:1420313; doi: 10.3389/fcell.2024.1420313 (2024).

Wenger V, Zeiser R: Deciphering the role of the major histocompatibility complex, the intestinal microbiome and metabolites in the pathogenesis of acute graft-versus-host disease. Best Pract Res Clin Haematol 37(3):101567; doi: 10.1016/j.beha.2024.101567 (2024).

Zimmermann JA, Lucht K, Stecher M, Badhan C, Glaser KM, Epple MW, Koch LR, Deboutte W, Manke T, Ebnet K, Brinkmann F, Fehler O, Vogl T, Schuster E-M, Bremser A, Buescher JM, Rambold AS: Functional multi-organelle units control inflammatory lipid metabolism of macrophages. Nat Cell Biol 26(8):1261-1273; doi: 10.1038/s41556-024-01457-0 (2024).

Rosmus D-D, Koch J, Hausmann A, Chiot A, Arnhold F, Masuda T, Kierdorf K, Marie S, Kuhrt H, Fröba J, Wolf J,
Boneva S, Gericke M, Ajami B, Prinz M, Lange C and Wieghofer P: Redefining the ontogeny of hyalocytes as yolk sac‑derived tissue‑resident macrophages of the vitreous body. J Neuroinflammation 21:168; doi: 10.1186/s12974-024-03110-x (2024).

Moeed A, Thilmany N, Beck F, Puthussery BK, Ortmann N, Haimovici A, Badr MT, Haghighi EB, Boerries M, Öllinger R, Rad R, Kirschnek S, Gentle IE, Donakonda S, Petric PP, Hummel JF, Pfaffendorf E, Zanetta P, Schell C Schwemmle M, Weber A, Häcker G: The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell Death Differ 31(7):924-937; doi: 10.1038/s41418-024-01320-7 (2024).